2-(3-Nitrophenyl)propanoic acid
2-(3-Nitrophenyl)propanoic acid
CAS: 103204-32-6
Molecular Formula: C10H11NO4
2-(3-Nitrophenyl)propanoic acid - Names and Identifiers
| Name | 2-(3-Nitrophenyl)propanoic acid |
| Synonyms | 2-(3-Nitrophenyl)propanoic acid 2-methyl-2-(3-nitrophenyl)propanoic acid Benzeneacetic acid, α,α-dimethyl-3-nitro- |
| CAS | 103204-32-6 |
2-(3-Nitrophenyl)propanoic acid - Physico-chemical Properties
| Molecular Formula | C10H11NO4 |
| Molar Mass | 209.2 |
| Storage Condition | Room Temprature |
2-(3-Nitrophenyl)propanoic acid - Introduction
2-(3-Nitrophenyl)propanoic acid is an organic compound with the chemical formula C10H11NO4. Its nature is as follows:
1. Appearance: 2-(3-Nitrophenyl)propanoic acid is a white crystalline solid.
2. Solubility: It is insoluble in water, but has good solubility in organic solvents such as methanol, ethanol and ether.
Applications of 2-(3-Nitrophenyl)propanoic acid include:
1. Chemical intermediates: it is an important organic synthesis intermediates, in the synthesis of drugs, dyes and heterocyclic compounds have a wide range of applications.
2. Dye: Due to its structural characteristics, it can be used for the preparation of dyes and the production of colorants.
3. Medical field: it is used in the field of medicine for the synthesis of specific drug molecules.
The methods for preparing 2-(3-Nitrophenyl)propanoic acid are mainly as follows:
1. Lai's thermal method: 2-methylacetone (2-methylpropanone) and 3-nitroacetophenone (3-nitrophenylacetone) react under Redox conditions to obtain 2-(3-Nitrophenyl)propanoic acid.
2. ASETR plasma-assisted nucleophilic substitution reaction: the nucleophilic substitution reaction is promoted by ASETR plasma, and 2-methyl -2-(3-nitrophenyl) acetone (2-(3-nitrophenyl)propanone) reaction with formic acid gives the target product.
3. Sodium azide treatment method: 2-methyl -2-(3-Nitrophenyl) acetone reacts with sodium azide to obtain 2-(3-Nitrophenyl)propanoic acid.
Regarding safety information, due to the lack of specific research data, the toxicity and harmfulness of 2-(3-Nitrophenyl)propanoic acid are not clear. Therefore, laboratory safety procedures should be followed when using or operating, and in a well-ventilated environment. At the same time, if contact with eyes, skin or inhalation into the respiratory tract, immediately rinse with plenty of water or seek medical help. Other Safety and Hazard information should be evaluated based on specific study data and material safety data sheets.
1. Appearance: 2-(3-Nitrophenyl)propanoic acid is a white crystalline solid.
2. Solubility: It is insoluble in water, but has good solubility in organic solvents such as methanol, ethanol and ether.
Applications of 2-(3-Nitrophenyl)propanoic acid include:
1. Chemical intermediates: it is an important organic synthesis intermediates, in the synthesis of drugs, dyes and heterocyclic compounds have a wide range of applications.
2. Dye: Due to its structural characteristics, it can be used for the preparation of dyes and the production of colorants.
3. Medical field: it is used in the field of medicine for the synthesis of specific drug molecules.
The methods for preparing 2-(3-Nitrophenyl)propanoic acid are mainly as follows:
1. Lai's thermal method: 2-methylacetone (2-methylpropanone) and 3-nitroacetophenone (3-nitrophenylacetone) react under Redox conditions to obtain 2-(3-Nitrophenyl)propanoic acid.
2. ASETR plasma-assisted nucleophilic substitution reaction: the nucleophilic substitution reaction is promoted by ASETR plasma, and 2-methyl -2-(3-nitrophenyl) acetone (2-(3-nitrophenyl)propanone) reaction with formic acid gives the target product.
3. Sodium azide treatment method: 2-methyl -2-(3-Nitrophenyl) acetone reacts with sodium azide to obtain 2-(3-Nitrophenyl)propanoic acid.
Regarding safety information, due to the lack of specific research data, the toxicity and harmfulness of 2-(3-Nitrophenyl)propanoic acid are not clear. Therefore, laboratory safety procedures should be followed when using or operating, and in a well-ventilated environment. At the same time, if contact with eyes, skin or inhalation into the respiratory tract, immediately rinse with plenty of water or seek medical help. Other Safety and Hazard information should be evaluated based on specific study data and material safety data sheets.
Last Update：2024-04-09 21:04:16
